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Gingivitis and periodontitis are inflammatory conditions of the oral cavity. They are characterized by bleeding, redness and tissue breakdown around the teeth.
The role of Hyaluronic Acid in managing inflammation of periodontal disease
Periodontal diseases are bacterially induced destructive conditions in which random bursts of accute inflammation occur in susceptible sites around the mouth.
Modern management of periodontal diseases
The adjunctive application of hyaluronan may have positive effects on probing depth
reduction and may prevent recolonization by periodontopathogens
Hyaluronic Acid as an adjunct after scaling and root planing – A prospective randomized clinical trial
Aim: To clinically and histopathologically evaluate the anti-inflammatory effect of 0.2% hyaluronan gel alone and …
Evaluation of hyaluronan gel (Gengigel) as a topical applicant in the treatment of gingivitis
The aim of this study was to evaluate the efficacy of a topical hyaluronic acid (HA) preparation (0.2%) in the management of …
The efficacy of topical Hyaluronic Acid in the management of recurrent aphthous ulceration
Abstract: Introduction: In implants, maintenance assumes an important role. The role of chlorhexidine (CHX) is well known in …
Peri-Implants maintenance of immediate function implants a pilot study comparing Hyaluronic Acid & Chlorhexidine
Hyaluronic acid application has been proven to be beneñcial in a number of medical disciplines. The aim of the current study …
Local application of Hyaluronan gel in conjunction with periodontal surgery_a randomized controlled trial
The aim of the present study was to evaluate the adjunctive effect of the local application of a hyaluronan gel to …
Local Delivery of Hyaluronan as an adjunct to scaling and root planning in the treatment of chronic periodontitis
Hyaluronic and (hyaluronan) is a glycosaminoglycan with anti-inflammatoryand antiedematous properties…
Treatment of gingivitis with Hyaluronan
Introduction Almost everything about hyaluronan is unusual; yet its extraordinary attributes derive from a chemical…
Hyaluronan in morphogenesis and remodeling
The present study was performed to evaluate the anti-ulcerogenic activity of hyaluronic acid against ethanol induced gastric…
Evaluation of Hyaluronate anti-ulcer activity against gastric mucosal injury
This investigation is one of series of projects seeking to ascertain whetther hyaluronic acid (HA) is therapeutically effective in…
Bacteriostatic effects of Hyaluronic Acid
After periodontal pocket debridement the application of Gengigel professional into the pocket produced a significant reduction of pocket depth.
Α comparison in postoperative healing of sites receiving non-surgical debridement augmented with and without a single application of hyaluronan 0.8 gel
The results indicate that Hyaluronan promotes wound healing and bone consolidation following tooth extraction. The result also suggests that Hyaluronan could be useful to cut down the interval between extraction and implantation.
Action of Hyaluronan Acid on the wound healing process following extraction
We investigate the expression of proteoglycans (PGs) and hyaluronan (HA) during healing of human mucosal wounds…
Expression of proteoglycans and hyaluronan during wound healing
Outcome: Gengigel-treated sites showed significantly greater improvement for bleeding on probing (BOP) (p<0.05) when compared with control sites. Probing depth also significantly improved compared with baseline and control (reduction of 1.0 ± 0.3mm, p<0.05). No improvement in clinical attachment level (CAL) for either group at 12w.
Clinical Paper: Gengigel – Periodontitis Trial 2009
Outcome: Application of topical HA produced a significant reduction (P < 0.05) in soreness scores when compared with placebo for up to 4 h post-application.
Clinical Paper: Gengigel – Lichen Planus
The results indicate that Hyaluronan promotes wound healing and bone consolidation
following tooth extraction.